"Explore the Mississippi" on the Great River Road in Illinois National Scenic Byway. On your 550 mile adventure along the western shores of Illinois, experience the rich Heritage, Agriculture, Sightseeing, Nature & Wildlife, and history along the way. Begin your adventure on the vast Great River Road in Illinois in East Dubuque being the furthest northern part of the road or at Cairo being the furthest southern part of the road, or anywhere in between. No matter where you begin, you will be sure to find some of the most beautiful and historical Bed and Breakfast, Hotels, Motels, and Resorts in the state!